San Francisco 49ers tight end George Kittle (illness) is cleared to play in Week 5 against the division-rival Seattle Seahawks, the team announced via the X platform on Sunday. Kittle was initially listed as having an illness, but was not on the inactive list an hour before kickoff against the Seahawks in Seattle. The veteran TE has tallied at least 70 yards in each of his last three games and has four touchdowns on the season. Kittle remains one of Brock Purdy's favorite targets and a key part of San Francisco's offense. He remains a high-end TE1 and a must-start against a tough divisional opponent.

Pittsburgh Steelers wide receiver Roman Wilson (hand) has been ruled out for the remainder of Sunday's Week 5 game against the Indianapolis Colts, according to Nick Farabaugh. Wilson finishes without a reception on one target after an apparent 11-yard catch late in the second quarter was overturned following a replay review. He entered Sunday with six receptions for 134 yards and two touchdowns over his previous two games. Pittsburgh was already without Michael Pittman Jr. (foot), who was placed on injured reserve Saturday.

Los Angeles Chargers wide receiver Ladd McConkey (foot) is active for Sunday's Week 5 game against the Denver Broncos but isn't expected to play meaningful snaps, according to Adam Schefter of ESPN. McConkey missed all three practices this week after aggravating his foot injury against Seattle, where he failed to catch either of his two targets. He's managed 12 receptions for 183 yards and a touchdown through four games. The Chargers are also without Quentin Johnston (chest) and Brenen Thompson (quadriceps), leaving Tre' Harris, Derius Davis and Marquez Valdes-Scantling among their available receiving options.

Houston Texans running back David Montgomery (groin) has been ruled out for the remainder of Sunday's Week 5 game against the Tennessee Titans, according to Adam Schefter of ESPN. Montgomery left during the second quarter and was initially questionable to return before being downgraded to out. He finishes with five carries for 11 yards and no receptions. Woody Marks had already been sharing backfield duties with Montgomery before the injury.