Entering 2026, Pittsburgh Steelers quarterback Aaron Rodgers is set to begin his 22nd NFL season. Across 16 games with the Steelers in 2025, the 42-year-old completed 65.7% of his pass attempts for 3,322 yards, 24 touchdowns, and seven interceptions. In Week 1, Pittsburgh will host the Atlanta Falcons. Atlanta fielded a mid-pack pass defense in 2025, finishing the year ranked 15th in the NFL in passing yards (3,773) and 20th in passing touchdowns (27) allowed. However, the Falcons are also set to start third-string quarterback Cooper Rush (back) against Pittsburgh on Sunday. As a result, the Steelers may choose to lean into a run-heavy attack in what projects to be an excellent matchup for their defense. Rodgers offers zero fantasy value as a rusher at this point in his career, so he needs a high volume of pass attempts to provide high-end fantasy production. In everything other than the deepest two-QB leagues, Rodgers profiles as a risky start for fantasy managers in Week 1.

Las Vegas Raiders running back Ashton Jeanty gave fantasy managers a scare when he suffered an ankle injury in a training camp practice late in the summer. However, the 22-year-old is off the injury report and will be active in the Raiders' season opener against the Miami Dolphins on Sunday. Jeanty operated as a three-down workhorse in 2025, recording 975 rushing yards, 346 receiving yards, and 10 touchdowns on 321 touches across 17 games. He's expected to play a similar role in 2026 and should have a better offensive ecosystem around him under the Raiders' new head coach and play-caller, Klint Kubiak. Jeanty also has a favorable matchup on paper in Week 1 against Miami, which allowed the seventh-most rushing yards (2,251) in the NFL in 2025. The Raiders may take a touch or two off of Jeanty's plate given the time he missed with the ankle injury, but he still profiles as a high-end RB2 option for fantasy managers in Week 1.

A fourth-round pick out of Arkansas, Las Vegas Raiders rookie running back Mike Washington Jr. recorded 1,296 scrimmage yards and nine touchdowns on 195 touches in his final collegiate season. After an impressive showing in the preseason, Washington Jr. is now set to open his first NFL season as the RB2 in Las Vegas behind star Raiders back Ashton Jeanty. When Jeanty is fully healthy, Washington Jr. may struggle to earn a fantasy-relevant workload. However, Jeanty suffered an ankle injury late in training camp that has limited his availability in practice over the last few weeks. While Jeanty will be active for the Raiders' season-opener against the Miami Dolphins on Sunday, Washington Jr. may see a few extra touches. In deeper league formats, Washington Jr. profiles as a low-end flex option in a favorable Week 1 matchup against Miami.

Las Vegas Raiders quarterback Kirk Cousins is ready to make his team debut against the Miami Dolphins on Sunday. The veteran quarterback will have a tough task ahead of him this weekend. The Raiders' top target, tight end Brock Bowers (knee) is ruled out for this game, which is bad news for this offense. Now, Cousins will need to rely on newcomer wide receiver Jalen Nailor, Tre Tucker, and backup tight end Michael Mayer as his primary targets. The 38-year-old can handle himself under center, but he can only do so much with the options that he has alongside him. Fantasy managers in one-quarterback leagues can avoid Cousins, but the veteran single-caller could be an option in superflex formats.