New England Patriots rookie running back TreVeyon Henderson took advantage of backfield mate Rhamondre Stevenson missing three games with a toe injury, compiling 264 rushing yards and four rushing touchdowns on 47 carries over that span. The 23-year-old second-rounder also added 10 catches on 12 targets for 66 yards and another TD. He had at least 14 rushing attempts in all three of those starts. Stevenson returned in the Week 12 win over the Cincinnati Bengals, but Henderson outsnapped him 46 to 22 and saw a healthy 18 carries for 66 yards, adding three receptions for 15 yards on four targets. Stevenson will continue to be involved if he's healthy in New England's backfield, but it looks like Henderson has finally taken over starting duties for the Pats as they head into a Monday night tilt against the Giants in Week 13. Against New York, Henderson will have clear RB1 upside in fantasy in a plus matchup.

Houston Texans quarterback Davis Mills has filled in nicely over the last three games with C.J. Stroud sidelined with a concussion. Mills has led the team to three wins, going 69-for-116 passing (59.5%) for 719 yards, five touchdowns, and one interception while also carrying the ball seven times for 38 yards and another score on the ground. He threw for over 250 yards in his first two starts, and he's tossed two TDs in two of his three starts. While the 27-year-old's fantasy stock has been on the rise as a short-term QB2 option in superflex leagues, he could be headed back to the bench this weekend when the team takes on the division-rival Indianapolis Colts on the road. Stroud remains in the league's concussion protocol, but he's practicing in full and is on track to be cleared to play this Sunday. If Stroud is cleared, Mills will head back to the bench in Week 13 and for the remainder of the season.

Detroit Lions offensive tackles Penei Sewell (ankle) and Taylor Decker (shoulder) are both active for the Thanksgiving Day game on Thursday against the division-rival Green Bay Packers in Week 13. Offensive guard Tate Ratledge (knee) will also be available. All three offensive linemen were listed as questionable on the final injury report. Sewell, the team's starting right tackle, has been playing through an ankle injury for the last three weeks but has not missed time. Decker has also been dealing with a shoulder injury for most of November, but he, too, has not missed any action. The 31-year-old veteran will continue to serve as Detroit's starting left tackle as he protects quarterback Jared Goff's blind side. Sewell and Decker will have their hands full against a strong Packers pass rush on Thursday.

Detroit Lions rookie wide receiver Isaac TeSlaa (hand), who was listed as questionable for Thursday's game, is officially active for the Thanksgiving Day tilt against the division-rival Green Bay Packers at Ford Field. TeSlaa has barely played in his first season in the NFL, but he's had a nose for the end zone, with two touchdown receptions on his four catches on the year. The 23-year-old third-rounder out of Arkansas could be in line for a season-high in snaps on Turkey Day, too, with Kalif Raymond (ankle) out, as well as tight ends Sam LaPorta (back, Injured Reserve) and Brock Wright (neck). TeSlaa's playing time should receive a boost, but fantasy managers should still consider him a highly volatile, touchdown-dependent flex option in deeper leagues. He's been targeted nine times all year and has 65 yards on his four receptions.