Philadelphia Eagles running back Saquon Barkley finished the 2025 season with 1413 scrimmage yards and nine touchdowns on 317 total attempts. After totaling nearly 2,300 scrimmage yards in 2024, Barkley regressed, dropping from 5.8 yards per carry to 4.1 this season. Despite the Eagles' offensive struggles this season, they are in the playoffs and hosting the San Francisco 49ers in the Wild Card Round. The 49ers allowed the 10th-most fantasy points to running backs this season, and injuries to their defensive line and linebackers should open up lanes for Barkley. The defending champions relied heavily on their star running back in last year's Super Bowl run, and they are expected to do the same as they chase back-to-back Super Bowl titles.

Philadelphia Eagles quarterback Jalen Hurts hopes to lead the Eagles to back-to-back Super Bowl titles this season. Hurts was solid in the regular season, throwing for 3,224 yards, a career-high 25 passing touchdowns, and just six interceptions (the fewest among any full-time starting quarterback in the NFL). The Eagles' offense has regressed under offensive coordinator Kevin Patullo, dropping from the seventh-ranked scoring offense in 2024 to 19th this season. While the offense has struggled this season, the Eagles are still hosting the San Francisco 49ers in the Wild Card round, a team that struggled against the pass toward the end of the season. In what could be a high-scoring affair, Hurts is among the top quarterbacks in fantasy this week and could be a great value against the injury-plagued 49ers' defense.

Green Bay Packers wide receiver Jayden Reed was held without a catch in Week 18's loss to the Minnesota Vikings, playing on just 16% of snaps. Reed dealt with injuries all season, from a foot fracture in training camp to a broken collarbone in Week 2. Reed finished his third season, playing seven games and averaging career lows in every major statistical category. Reed has a chance to right his wrongs in the Wild Card round against the Chicago Bears, but it could be challenging with slot cornerback Kyler Gordon possibly being activated off injured reserve. If the Packers want to win this game against the NFC North champions, they will need to run the ball, which could limit Reed's opportunities in the passing game. The third-year receiver is a low-end WR2 this week and is very risky given his regular-season struggles.

Los Angeles Chargers tight end Oronde Gadsden has been inconsistent down the stretch, but he still exceeded expectations as a fifth-round rookie. Gadsden brought in 49 catches (69 targets) for 664 yards and three touchdowns in 15 games. The Syracuse product had a historic stretch early in the season once he earned a full-time role in Week 6, posting his most receiving yards ever by a rookie tight end over a four-game span. He also became the first rookie tight end with four straight games of 65 or more receiving yards. Gadsden's production faded down the stretch, as he averaged just two catches (3.3 targets) for 26.2 yards per game with one touchdown over the final six weeks. Gadsden is a risky option for Sunday night's Wild-Card game against the New England Patriots, with New England being a slightly favorable matchup for opposing tight ends, allowing the 11th-most catches per game (5.7) and the 12th-most yards (57.1).