Detroit Lions wide receiver Amon-Ra St. Brown had one of the least efficient games of his career in his team's Week 11 loss to the Philadelphia Eagles, hauling in just two of 12 targets for 42 yards. On paper, St. Brown has a much more favorable matchup in Week 12 against the New York Giants. Through 11 weeks, New York has allowed the sixth-most passing yards (2,641) and seventh-most passing touchdowns (19) in the NFL. St. Brown has earned double-digit targets in four out of his last five games and should continue to see a heavy workload in Week 12 with Lions tight end Sam LaPorta (back) sidelined by a back injury. If there's one concern for St. Brown, it's that he's struggled with drops in recent weeks and holds a career-high 5.3% drop rate in 2025. Still, the 26-year-old has been one of the most reliable wideouts in the NFL over the course of his career and remains a must-start fantasy wide receiver in Week 12.

Carolina Panthers running back Trevor Etienne has essentially been a non-factor lately. He didn't log a snap in Week 10, and he played just four snaps with one carry last Sunday against the Atlanta Falcons. The rookie has primarily played on special teams, logging either a kick or punt return in all but one game this year. In total, he has just 20 carries for 94 rushing yards in 2025, plus two catches for an additional nine yards. He also fumbled once. Most of his volume came during Weeks 4-6 when Chuba Hubbard was banged up. As long as Hubbard and Rico Dowdle are healthy, Etienne will be a non-factor on offense. Managers should continue to patiently stash him in dynasty leagues, but they can leave him on waivers in redraft formats. That remains true in Week 12 against the San Francisco 49ers.

Detroit Lions quarterback Jared Goff had one of his worst games in a Lions uniform in Week 11, completing just 14 of 37 pass attempts for 255 yards, one touchdown, and one interception in a loss to the Philadelphia Eagles. On paper, Goff has a much easier matchup in Week 12 when Detroit hosts the New York Giants. Through 11 weeks, the Giants have allowed the sixth-most passing yards (2,641) in the NFL. New York will also remain without cornerback Paulson Adebo (knee), who has been out since Week 7 with a knee injury. The Lions are dealing with some health issues themselves, as Goff will be without tight end Sam LaPorta (back), and multiple Detroit offensive linemen are playing through nagging injuries. Still, Goff could have a chance to do damage against the struggling Giants defense and profiles as a must-start fantasy QB1 in Week 12.

New York Jets wide receiver Allen Lazard (coach's decision) has been inactive for the last two weeks, and he's trending toward being a healthy scratch again in Week 12 against the Baltimore Ravens. Lazard went from playing 78 percent of the snaps in Week 8 to being a healthy scratch for the Jets' next game, and he has been inactive ever since, even with the Jets trying to find ways to replace Garrett Wilson (knee). So far, Adonai Mitchell, John Metchie III, Tyler Johnson, Arian Smith, and Isaiah Williams have been the Jets' preferred replacements for Wilson, leaving Lazard as the odd man out. With all five of those receivers healthy, it looks like Lazard is heading for more of the same. Don't expect him to suit up against Baltimore.