Arizona Cardinals running back James Conner (foot) was placed on the Injured Reserve to begin the season. He continues to have issues with a foot injury that ended his 2025 season. Conner will miss at least the first four games of the season while he recovers from that. Once he's back, there might not be a significant role in the backfield for Conner. Rookie Jeremiah Love (ankle) figures to play a big part in the running back once he's back to full speed. The Cardinals also signed Tyler Allgeier to a two-year deal during the offseason. Conner figures to have some kind of role once he's healthy, but he isn't someone who needs to be selected in redraft formats to begin the season. He could be worth stashing on the IR, but who knows what kind of role he'll have in the mess of this backfield.

Los Angeles Chargers running back Kimani Vidal has reportedly been the best pass-protector in the backfield during camp, according to Alexander Insdorf. Vidal won't be the starter, but that doesn't mean that he won't have a significant role in the offense this season. His above-average pass-blocking abilities could get him on the field more frequently than fantasy managers might think. Omarion Hampton is the starter, but Vidal could have an advantage over Keaton Mitchell (knee) for the No. 2 role in the backfield. Vidal might be fantasy relevant outside of being the handcuff to Hampton. He's worth stashing for fantasy managers seeking additional depth in the backfield.

Minnesota Vikings running back Demond Claiborne was unlikely to make a legitimate push for playing time this summer. The 22-year-old was likely always going to be a depth option after being taken in the sixth-round by the Vikings during this year's draft. Claiborne did little to impress during the preseason, and he appears to have himself locked into the RB3 role in Minnesota. There probably won't be room for much action with Aaron Jones Sr. and Jordan Mason leading the way in the running game. His only chance at seeing serious playing time would be if one of the backs goes down with an injury. He is best left on the waiver wire in redraft formats to begin the year.

Denver Broncos wide receiver Marvin Mims Jr. might have taken a step back on the depth chart. The 24-year-old appears to have lost the No. 3 wideout battle to Pat Bryant during the summer. Bryant posted a decent rookie campaign and appears to have secured himself a starting gig to begin the season. Mims will likely take a step back and play more of a reserve role to start the season, which makes him a shaky option in redrafts. The Broncos already have Jaylen Waddle and Courtland Sutton as their primary passing options. There might not be enough room for Mims to be a serious threat this upcoming season.