San Francisco 49ers pass-rusher Nick Bosa (calf) is unlikely to suit up for the upcoming Week 5 matchup against the Seattle Seahawks, per Cam Inman of The San Jose Mercury News. Bosa has missed two games in a row due to a strained calf that he suffered during practice. It looks like Bosa is trending towards missing a third game in a row as he continues to nurse this lingering calf issue. His absence will certainly hurt this defensive unit as they head into a big divisional game against the Seahawks. Ogbo Okoronkwo and Keion White will likely be asked to step up if Bosa is unlikely to go this weekend.

Washington Commanders running back Rachaad White (shoulder) is expected to get back on the practice field this week, per Tashan Reed. Head coach Dan Quinn believes White will be able to practice this week after missing practice all last week due to a lingering shoulder issue. White sat out during Sunday's game against the Indianapolis Colts, but he has a chance to return for the Week 5 matchup against the New York Giants. If he remains out, Jacory Croskey-Merritt will handle the bulk of the rushing attempts with Austin Ekeler and Kaytron Allen mixing in as well. Fantasy managers should check back on White's status once they begin practicing again on Wednesday.

Washington Commanders head coach Dan Quinn said on Monday that the team is still evaluating what wide receiver Terry McLaurin (hamstring) will be able to do during Wednesday's practice, per John Keim. McLaurin popped up on the injury report with a hamstring issue last Friday. He was ultimately unable to suit up against the Indianapolis Colts in Week 4. McLaurin reportedly pushed to play, but the Commanders decided to play it safe with the veteran wideout. It sounds like McLaurin is day-to-day, but the Commanders should give more information once they begin practicing on Wednesday. For now, fantasy managers should consider McLaurin as questionable ahead of the Week 5 matchup against the New York Giants.

Green Bay Packers running back MarShawn Lloyd was significantly involved during Sunday's win over the Tampa Bay Buccaneers. Lloyd carried the ball seven times for 13 yards, while hauling in all five targets for an additional 36 yards through the air. That was the most Lloyd has been involved in the passing game this season. His role in the backfield could be expanded going forward, with fellow back Chris Brooks (ankle) leaving early in Week 4. If Brooks is unable to play in Week 5, Lloyd could end up being an interesting flex option in deep leagues against the Chicago Bears.