Cincinnati Bengals running back Tahj Brooks was hardly utilized in his team's Week 1 win over the Tampa Bay Buccaneers, logging just two snaps on offense and failing to record a touch. A sixth-round pick in the 2025 NFL Draft, Brooks recorded just 54 scrimmage yards on 17 touches across 16 games as a rookie. Fast forward to 2026, and Brooks remains buried on the Bengals running back depth chart behind star back Chase Brown and trusted veteran Samaje Perine. While Brooks may be a more explosive rusher than the 31-year-old Perine, Perine is widely thought of as one of the league's best pass-protectors at the running back position and also recorded three catches for 30 yards in Week 1. Barring an injury or a change of scenery, Brooks should remain off the radar of fantasy managers heading into Cincinnati's Week 2 matchup against the Houston Texans.

Buffalo Bills running back James Cook III put up a huge game in his team's 41-31 Week 2 win over the Detroit Lions, recording 21 carries for 135 yards and a touchdown. It was a nice bounce-back performance for the 26-year-old, who was held to 69 yards from scrimmage on 16 touches by the Houston Texans in Buffalo's season-opener. Cook III's fantasy production is impacted by the presence of Bills quarterback Josh Allen, who had two rushing touchdowns against Detroit and continues to be Buffalo's preferred option in short-yardage situations. Still, Cook III was the only Bills running back to receive a carry in Week 2, even in a game that his team largely controlled for 60 minutes. Buffalo's offense also looks like one of the best units in football so far, which should give Cook III plenty of chances to score touchdowns. Entering the Bills' Week 3 matchup against the Los Angeles Chargers, Cook III remains a clear fantasy RB1.

Buffalo Bills tight end Dalton Kincaid turned in a dominant performance in his team's 41-31 Week 2 win over the Detroit Lions, recording seven catches for 95 yards and a touchdown on eight targets. The 26-year-old is off to an excellent start to the 2026 season, hauling in 12 catches for 225 yards and a score on 14 targets across his team's first two games. While Kincaid was highly efficient as a receiver in 2025, he saw just 49 targets across 12 games. He missed five games due to injury, and the Bills limited his workload even in the weeks when he was active. Kincaid appears to be fully healthy in 2026, and he's played at least 66% of Buffalo's offensive snaps in both Week 1 and Week 2. With top Bills wide receiver DJ Moore (shoulder) now battling an AC joint sprain that could cause him to miss time, Kincaid's usage could grow even further in Buffalo's Week 3 matchup against the Los Angeles Chargers. As long as he remains healthy, Kincaid profiles as a must-start tight end for fantasy managers.

Detroit Lions wide receiver Amon-Ra St. Brown was one of the lone bright spots in his team's 41-31 Week 2 loss to the Buffalo Bills, recording nine catches for 142 yards and two touchdowns on 13 targets. St. Brown has gotten off to a fantastic start to the season, hauling in 19 receptions for 209 yards and four touchdowns on 27 targets across Detroit's first two games. The 26-year-old has been a highly reliable wide receiver for fantasy managers for a number of years now, posting three consecutive seasons with at least 115 catches, 1,250 receiving yards, and 10 touchdowns coming into 2026. Still, he could be poised for a career season from a production perspective if the Lions' defense continues to struggle as mightily as it has through the first two weeks. Heading into Detroit's Week 3 matchup against the New York Jets, St. Brown profiles as a high-end fantasy WR1.