Philadelphia 76ers guard Anfernee Simons (hamstring) isn't expected to play in the team's next two preseason games due to right hamstring tightness, per Dave McMenamin of ESPN.com. Simons also missed Monday's preseason opener against the Knicks. The 27-year-old's next opportunity to suit up will come on Oct. 16 against the Celtics. He averaged 14.3 points, 2.5 rebounds, and 2.4 assists across 55 games last season. Simons could see an uptick in fantasy value if injuries create additional opportunities in Philadelphia's backcourt.

According to Dave McMenamin of ESPN, Philadelphia 76ers forward Dominick Barlow (back) will miss the next two preseason games. Barlow also missed the Sixers' preseason opener against the Knicks on Monday due to a back issue. Barlow is coming off his best campaign, averaging 7.7 points, 4.8 rebounds, and 1.2 assists in 23.8 minutes per game across 71 contests last season. He next gets a chance to see preseason action on Oct. 16 against the Celtics.

Hunter Patterson of The Athletic reports that Detroit Pistons center Jalen Duren is expected to suit up at some point this preseason. The 22-year-old big man recently agreed to a five-year, $200 million fully guaranteed contract to return to the Motor City, ending a prolonged restricted free agency standoff. Duren came into his own in 2025-26, averaging 19.5 points and 10.5 rebounds on 65.0 percent shooting in 70 starts. With Isaiah Stewart dealt to Memphis in June, Duren should face little competition for center minutes, as John Collins projects as the main frontcourt alternative. His next chance to take the floor is on Saturday against the Wizards.

According to Chris Haynes of NBA TV, Utah Jazz center Jusuf Nurkic (foot) will miss at least four weeks after suffering a partial plantar plate tear in the second toe of his right foot. The 32-year-old big man was projected to open the season as Utah's starting center but will now miss the start of the regular season. In his absence, Jaren Jackson Jr. could see additional minutes at center, while Mo Bamba and Jaxson Hayes may also take on expanded frontcourt roles.