Oklahoma City Thunder forward/center Chet Holmgren (knee) has been ruled out for Wednesday's game against the Dallas Mavericks with right patellar tendinitis. It will be his second straight absence after averaging 12.0 points, 9.3 rebounds, and 3.0 blocks through three games. Isaiah Hartenstein should continue to handle the bulk of the center minutes, while rookie Aday Mara is worth a look after posting 11 points, 10 rebounds, two assists, and two blocks in 20 minutes against Phoenix. Kenrich Williams should also stay more involved in the frontcourt, but Mara's rebounding and shot-blocking give him the stronger short-term fantasy appeal.

Houston Rockets forward/center Alperen Sengun (back) has been ruled out for Wednesday's road game against the Milwaukee Bucks with low back soreness. It will be his first absence of the season after averaging 24.5 points, 9.0 rebounds, and 7.0 assists on 58.1% shooting during Houston's 4-0 start. With Steven Adams (soleus) also sidelined, Clint Capela is in line for a much larger role at center, while Tari Eason and Jabari Smith Jr. could pick up additional frontcourt work. Sengun's next chance to return comes Friday in Dallas.

New Orleans Pelicans center Yves Missi (knee) has been ruled out for Wednesday's game against the Denver Nuggets with a left knee bone bruise. Missi has been sidelined since injuring his knee Friday against Utah and remains without a return timetable. The 22-year-old opened the season with 13 points, 14 rebounds, five assists, three blocks, and two steals against Indiana. Derik Queen has stepped up in his absence, finishing with 17 points and eight rebounds on 6-for-10 shooting Saturday in Denver. DeAndre Jordan should remain part of the center rotation, but Queen offers considerably more fantasy upside while Missi is sidelined.

Portland Trail Blazers guard Scoot Henderson (ankle) is available for Tuesday's game against the Los Angeles Lakers after dealing with left ankle soreness. The 22-year-old has come off the bench through Portland's first two games, averaging 9.5 points, 1.5 rebounds, and 1.5 assists in 20.0 minutes while shooting 1-for-9 from three. Henderson averaged 14.2 points and 3.7 assists across 30 appearances last season, but a backcourt featuring Damian Lillard, Ja Morant, and Jrue Holiday leaves little room for a major fantasy role unless injuries open up more minutes.