Brad Keselowski of RFK Racing had high hopes for a strong performance at Talladega Superspeedway, but ended with disappointment through a finish of 36th during Sunday's Jack Link's 500. Beginning the race from the 22nd position, Keselowski quickly made his way up through the field at the start of the first stage. The No. 6 Ford driver made it as high as the top three, but never made it to the lead. After riding with the pack for most of the first stage, the first round of pit stops came up, and Keselowski looked to pit with other Ford drivers on lap 43. Unfortunately, Kyle Busch got up to the side of Keselowski and lost control of his car, colliding with the No. 6 Ford and causing a multi-car crash. Keselowski sustained too much damage from this incident and was unable to continue, settling for a 36th-place finish, his worst result at Talladega since October 2016, when he failed to finish due to an engine failure.

Hendrick Motorsports driver Kyle Larson finished Sunday's Jack Link's 500 at Talladega Superspeedway in the second position. Starting from the 25th position, Larson quietly kept up with the pack for most of the first stage and kept his car clean. After executing on some pit strategy to gain track position by lap 49, Larson made a run to the front and got there with some drafting help, as he ended up winning the first stage, collecting plenty of stage points. In the second stage, Larson remained in the front half of the pack, running inside the top 10 for most of the stage. He ultimately fell just short of winning the second stage, finishing second and earning more stage points. In the final stage, Larson went up and down through the pack as green flag racing and pit stops shuffled the field. However, by the end of the race, Larson came back and was in position to steal a win. On the final lap, Larson was behind Austin Cindric and spent the lap pushing him ahead to the victory. The No. 5 Chevrolet driver was initially scored with a third-place finish, but Ryan Preece, who finished ahead of Larson, was disqualified in post-race inspection. As a result, Larson was credited with a finish of second, a new career-best finish on a drafting track.

Team Penske's Ryan Blaney looked to have a quality finish for the Jack Link's 500 at Talladega Superspeedway on Sunday, but left the race early after unfortunate circumstances. In the first stage, Blaney started from the ninth position, but quickly shuffled back to the middle part of the pack as other racers passed him. The No. 12 Ford driver then rode around until pit stops were occurring around laps 41-43. On lap 43, Kyle Busch tried merging onto pit road but lost control of his car, making contact with Brad Keselowski, who went up the track and in front of Blaney. With no place to go to avoid crashing, Blaney suffered damage and had to be towed back to the garage. Although his team attempted to repair the damage on Blaney's car, they decided the damage was too severe to repair, leaving Blaney out of the race. Blaney would end up placing 37th with a DNF due to an accident for the second consecutive Talladega race.

William Byron of Hendrick Motorsports had an up-and-down day during the Jack Link's 500 at Talladega Superspeedway. Beginning the race from the 16th position, Byron quietly rode with the pack during the race's first stage until the first set of pit stops. Byron had his first pit stop under caution after a few other drivers crashed, but gained track position as a result. Byron made a run towards the front with his teammate Kyle Larson, ending the first stage in second and scoring nine stage points. In the second stage, Byron remained competitive, challenging for the lead in a few instances until he experienced steering issues. This caused him to drop back in the pack and end stage two in 18th, making him unable to earn further stage points. In the final stage, Byron's team addressed the steering issues and returned to the front by the end of the race, thanks to effective pit strategy and gradual track position gains. Byron was in a position to compete for the win, pushing Ryan Preece, but settled for what was initially a fourth-place finish. Preece would end up getting disqualified in post-race inspection, crediting Byron with a finish of third in Sunday's event. This finish continues a streak of what is now five consecutive top-10 finishes at Talladega for Byron.