Arizona Diamondbacks shortstop Geraldo Perdomo (ankle) was removed from Saturday's game against the San Diego Padres with a left ankle sprain. He injured his ankle while fielding a ground ball during the seventh inning. The 26-year-old went 0-for-3 with a strikeout before exiting. He is considered day-to-day with his next chance to return being on Sunday in the series finale against the Padres in Mexico City. Perdomo is slashing .250/.350/.393 with a home run and six stolen bases over 84 at-bats this season. Ildemaro Vargas would see an uptick in at-bats and would handle shortstop for the Diamondbacks if Perdomo misses any time. Vargas is off to a hot start this season, hitting .351 (26-for-74) with five home runs and 16 RBI over 19 games.

Arizona Diamondbacks right-hander Zac Gallen (shoulder) was removed from Saturday's start against the San Diego Padres with a right shoulder contusion. He was hit by a comebacker in the shoulder during the third inning and initially stayed in the game. The Diamondbacks pulled Gallen at the end of the third inning after 49 pitches. He allowed one hit while striking out three over three scoreless innings before exiting. The 30-year-old is considered day-to-day and will undergo additional testing. Overall, he owns a 3.14 ERA, 1.36 WHIP, and 17 strikeouts over 28 2/3 innings in 2026. Gallen is considered questionable to make his next start on Friday at Wrigley Field against the Chicago Cubs.

Toronto Blue Jays relief pitcher Louis Varland was tasked with holding the lead in the ninth inning during Saturday's game against the Cleveland Guardians. This one nearly slipped away from Varland, but he was able to hold it down in the end. He allowed three hits, one earned run, one walk, and struck out two batters on his way to his second save of the season. This outing was the first time that Varland had allowed a run all season long. He's likely the favorite to record saves in Toronto, with Jeff Hoffman being pulled out of the role earlier this week. Fantasy managers who are searching for a source of saves should consider adding Varland right now.

Atlanta Braves outfielder Michael Harris II (quad) is back in the starting lineup ahead of Saturday's game against the Philadelphia Phillies. Harris made an early exit from Thursday's game due to left quad tightness. He was originally penciled into the lineup on Friday, but was scratched due to the injury. He was able to come into the game as a pinch hitter and appears to be fully healthy now. Harris will serve as the designated hitter and bat fifth against right-hander Zack Wheeler on Saturday. Fantasy managers should adjust their lineups accordingly ahead of first pitch.