The Los Angeles Angels have placed starting pitcher Alek Manoah (finger) on the 15-day injured list due to a fingernail issue, per Jack Janes of The Sporting Tribune. Had he been healthy, Manoah may have broken camp as a member of the Angels' Opening Day starting rotation, particularly with fellow Angels starter Grayson Rodriguez (arm) also opening the year on the injured list. The 28-year-old Manoah is attempting to resurrect his career in Los Angeles after being waived by the Toronto Blue Jays last September. Manoah finished third in the American League Cy Young vote while pitching for Toronto in 2022, but has battled injuries and ineffectiveness ever since. He opened the 2025 season rehabbing an elbow injury and never made it to the big leagues, finishing the year with a 3.96 ERA and 1.53 WHIP across 38 2/3 minor league innings (10 starts). Manoah struggled mightily in Cactus League action for the Angels before getting injured, allowing 14 walks and five home runs across 15 1/3 innings pitched. Manoah will need to show a sustained run of both health and production before he's worthy of fantasy consideration in the majority of league formats.

Cincinnati Reds starting pitcher Nick Lodolo (finger) will open 2026 on the injured list due to a blister on his left index finger, per Gordon Wittenmyer of the Cincinnati Enquirer. Lodolo enjoyed a breakout season in 2025, posting a 9-8 record with a 3.33 ERA, 1.08 WHIP, and 156 strikeouts across 156 2/3 innings (28 starts). However, the 28-year-old has battled injuries throughout his career and is no stranger to finger ailments specifically, which caused him to miss time in both 2024 and 2025. Without Lodolo and star right-hander Hunter Greene (elbow) to open the year, the Reds will likely be relying on starting pitchers Rhett Lowder and Brandon Williamson at the back end of their rotation. Lodolo's current ailment may not ultimately cause him to miss much time, but his continued issues with blisters are a red flag for fantasy managers to be aware of.

ESPN's Jeff Passan reports that the Chicago Cubs extension agreement with outfielder Pete Crow-Armstrong is worth $115 million over six years and will start in 2027. Passan also notes that the deal does not include a club option, allowing Crow-Armstrong to hit free agency ahead of his age-31 season in 2033. The 24-year-old enjoyed a breakout campaign in 2025, hitting .247/.287/.481 with 31 home runs, 95 RBI, 91 runs scored, and 35 stolen bases across 647 plate appearances. Crow-Armstrong's profile is not without flaws, as he walked at just a 4.9% rate in 2025 and owns a .591 OPS across 284 career plate appearances against left-handed pitching. Still, Crow-Armstrong's elite center field defense guarantees him playing time, and his combination of power and speed provides him plenty of fantasy upside. The Cubs' financial commitment to Crow-Armstrong should only strengthen his already stellar dynasty outlook.

The Los Angeles Angels have placed second baseman Vaughn Grissom (hand) on the 10-day Injured List to open 2026, per Jack Janes of The Sporting Tribune. Janes reports that Angels manager Kurt Suzuki said Grissom is "progressing well" from the hand injury he suffered in a Cactus League game in mid-March. Grissom spent all of the 2025 season in the minor leagues, hitting .270/.342/.441 with 13 home runs, 48 RBI, 69 runs scored, and nine stolen bases across 418 Triple-A plate appearances as a member of the Boston Red Sox organization. If healthy, Grissom might have had a chance to challenge veteran journeyman Adam Frazier for the starting second base job with the Halos. Upon his return, Grissom will likely be battling Frazier and utility infielder Oswald Peraza for a spot on the Angels' active roster. However, Grissom should remain off the radar of fantasy managers for the time being.