Pittsburgh Pirates starting pitcher Jared Jones (elbow) threw 54 pitches across three innings of work in a rehab start with Triple-A Indianapolis on Wednesday, allowing five hits, one earned run, and one walk while striking out two. It was the second rehab start for Jones as he works his way back from internal brace surgery on his right elbow. The 24-year-old has not appeared in an MLB game since September 2024, but he appears to be progressing towards a return to the big leagues in the not-too-distant future. Jones flashed significant upside as a rookie in 2024, posting a 6-8 record with a 4.14 ERA, 1.19 WHIP, and 132 strikeouts across 121 2/3 innings (22 starts). He's currently on the 60-day injured list, so a late-May/early-June return for Jones is likely the plan in Pittsburgh. Fantasy managers should consider stashing Jones off the waiver wire now in leagues where he is available.

New York Mets manager Carlos Mendoza said that starting pitcher Kodai Senga (back) played catch on Wednesday and is feeling "a lot better," per Laura Albanese of Newsday. Senga was placed on the 15-day injured list in late April after receiving an epidural injection to treat lumbar spine inflammation. The 33-year-old was off to a terrible start to the 2026 season before hitting the IL, recording a 0-4 record with a 9.00 ERA, 1.95 WHIP, and 23 strikeouts across five starts (20 innings). Senga was initially shut down from throwing, but it appears as though he's now progressing towards a return. Injuries have been a persistent issue for Senga, who has now thrown just 138 2/3 innings since the start of the 2024 season. Given his spotty health track record and his ineffectiveness this season, Senga can likely be dropped in most fantasy formats.

Toronto Blue Jays manager John Schneider said that starting pitcher Shane Bieber (elbow) threw a bullpen on Wednesday and "looked sharp," per Mitch Bannon of The Athletic. Bannon reports that Bieber is scheduled to throw another bullpen next week before progressing to work against live hitters. The veteran right-hander has yet to pitch in 2026 as he works his way back from elbow and forearm issues that landed him on the 60-day injured list before the start of the season. Bieber underwent Tommy John surgery in April 2024, which kept him out until August 2025. He was effective down the stretch for Toronto, recording a 4-2 record with a 3.57 ERA, 1.02 WHIP, and 37 strikeouts across 40 1/3 innings (seven starts). While Bieber is not eligible to return from the injured list until late May at the earliest, it appears that he's slowly making progress. Once healthy, he should be rostered in most fantasy formats.

San Francisco Giants starting pitcher Logan Webb (knee) is undergoing further evaluation on his left knee after exiting early from his start on Tuesday night against the San Diego Padres. After the game, Webb said that he has been dealing with discomfort in the knee for "a little while." The 29-year-old is off to a very slow start to 2026, as he's posted a 2-4 record with a 5.06 ERA, 1.40 WHIP, and 42 strikeouts across 48 innings (eight starts). The knee issues could provide an explanation for Webb's struggles. While Webb downplayed the injury after his start on Tuesday, it appears as though the team is seeking an exact diagnosis, and a trip to the injured list could be on the table. Should Webb miss time, right-hander Trevor McDonald could be the favorite to take his spot in the Giants' rotation.