Cincinnati Reds closer Emilio Pagan (hamstring) was carted off from his team's game against the Chicago Cubs on Tuesday night after one pitch and was clutching his left hamstring, according to Gordon Wittenmeyer of the Cincinnati Enquirer. Wittenmeyer notes that Pagan has been dealing with tightness in the hamstring this season but has avoided a trip to the injured list to this point. Entering play on Tuesday, Pagan had pitched to a 6.43 ERA and 1.43 WHIP with 11 strikeouts, six saves, and three blown saves across 14 innings in 2026. He may have been in danger of losing the ninth-inning role in Cincinnati for performance reasons anyway, but it seems as though Pagan could now miss time due to injury. If Pagan does end up on the injured list, Reds right-handers Tony Santillan and Graham Ashcraft could be the favorites to assume the closer role in Cincinnati.

Houston Astros closer Josh Hader (biceps) threw a scoreless inning with a walk and a strikeout in his rehab appearance with Triple-A Sugar Land on Tuesday. The 32-year-old is on the 60-day injured list due to a biceps injury, which means he is not eligible to make his return to Houston until late May. Still, it's a positive sign that Hader is taking steps in his progression back to the big leagues. Hader was dominant for the Astros in 2025, pitching to a 2.05 ERA and 0.85 WHIP with 76 strikeouts and 28 saves across 52 2/3 innings. Houston has struggled to fill the closer role in Hader's absence, with right-hander Enyel De Los Santos currently leading the team with three saves. Upon his return, Hader should immediately re-assume the ninth-inning role for the Astros.

New York Yankees starting pitcher Carlos Rodon (elbow) threw 83 pitches across 6 1/3 innings in a rehab start with Triple-A Scranton Wilkes-Barre on Tuesday. The veteran left-hander struggled, allowing seven hits, five earned runs, and two walks while recording four strikeouts. Still, Rodon has now thrown 16 innings across three rehab outings as he works his way back from offseason elbow surgery. If he comes through this outing without any issues over the next few days, Rodon's next start could come in the big leagues. The 33-year-old was excellent for the Yankees in 2025, recording an 18-9 record with a 3.09 ERA, 1.05 WHIP, and 203 strikeouts across 195 1/3 innings (33 starts). Upon his return, Rodon should be rostered in all fantasy formats.

New York Yankees starting pitcher Gerrit Cole (elbow) struggled in his rehab outing with High-A Hudson Valley on Tuesday, allowing seven hits and five earned runs across 4 1/3 innings. Cole threw 69 pitches, recording four strikeouts without walking a batter. The veteran right-hander has now made four rehab starts as he works his way back from Tommy John surgery, which caused him to miss the entire 2025 season. Cole was placed on the 15-day injured list before the start of 2026 and is eligible to be activated at any point, but the Yankees said before his start on Tuesday that he's still a little ways away from returning to the big leagues. Cole was an effective pitcher in 2024, pitching to an 8-5 record with a 3.41 ERA, 1.13 WHIP, and 99 strikeouts across 95 innings (17 starts). He may no longer be the Cy Young candidate he once was at his peak, but Cole should still provide fantasy-relevant production upon his return to the Yankees.